Comfortis is an oral flea control tablet that is manufactured by Elanco Animal Health, a subdivision of Eli Lilly and Company. Eli Lilly and Company was first founded in 1876. The company is based out of Indianapolis, Indiana, and was originally founded by Colonel Eli Lilly. Eli Lilly was 38 years old when he first organized the company and was initially interested in providing pharmaceutical products. The Eli Lilly Company currently conducts research in more than fifty different countries, and has nearly 40,000 employees worldwide. Elanco Animal Health is headquartered in Greenfield, Inidiana, and has direct associations with Eli Lilly and Company. Elanco is also partnered with Ivy Animal Health, which is also a company focused on the animal health industry. Elanco first introduced a product for veterinary use in 1953, and has continued their research program to develop new veterinary pharmaceutical products. Comfortis flea control product is only one of the many products currently produced by Elanco Animal Health.

Comfortis Active Ingredient

The active ingredient in Comfortis flea control formula is called Spinosad. Spinosad has two different chemical components called spinosyn A and spinosyn D. Spinosad is classified as a new group of insecticides that has recently been registered by the EPA (Environmental Protection Agency) as an environmentally conscious way to control many different insect populations. The active component in Spinosad is actually derived from a rare actinomycete bacterium that was first discovered in the soil of a Caribbean Island. This active component has never again been found in nature, and the bacterium that contains it was named Saccharopolyspora spinosa. The main advantage of Spinosad is that it combines the effectiveness of a synthetic insecticide with the benefits associated with a biological pest control organism. Spinosad kills fleas by causing agitation of a flea’s central nervous system, which causes death approximately 1 to 2 days after the flea ingests the substance. As of right now, Spinosad is highly valued in resistance management programs, since it has a very unique mode of action against insects.

Comfortis Product Information

There are several different side effects that may manifest after an animal ingests Comfortis oral tablets. The most common side effect is vomiting, with other side effects including lethargy, diarrhea, coughing, skin rash, hyperactivity, decreased appetite and excessive salivation. Unlike some other oral flea medications, Comfortis is effective at controlling flea infestations for approximately one month for dogs.

Comfortis Customer Reviews And Ratings

Most customer reviews about Comfortis cite it as being a very effective flea control product for dogs. However, the side effects of the product did cause concern among some consumers. Since extreme lethargy can be a side effect of Comfortis, this can cause dogs to become limp and unresponsive approximately two to four hours after the formula is ingested. This can be a very scary experience to witness, though it is very important to be familiar with all possible side effects before using this product for any pet. Comfortis is a systemic formula, and because of that, some pet owners seem to be initially reluctant to try it on their pets.

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